I don’t know if I’d call it ‘more intelligent’, but Colemak maintains most Windows hotkeys which imo makes it easier to use as anything but a typist. It also natively supports all diacritics, which Dvorak doesn’t.

The fundamental difference is that Dvorak focuses on alternating hands pressing keys while Colemak focuses on avoiding same-finger key presses while keeping the fingers on the home row as much as possible. You can read more about it on the official site.

I’ve used QWERTY, Dvorak, and Colemak and Colemak is by far my favorite.