Thats super interesring. It always amazes me how a small modification like a methyl group can so drastically alter the psychoactive properties of a substance. The body is such a nuanced and complicated system, its fascinating.

I really hope drug laws change so that we can see more research being done. Things like this help us learn more about not just the sustance, but the way our chemisty works & how our concious experience is shaped.

If you have any cool links on this topic, id love to browse them. Either way thanks for your run down on methyl groups :)