I’m by no means an expert, and have a similar amount of play time. I opted to push through the main story since all quests scale the same and you need to get to Act IV to unlock the horse.
I’m just now doing some of the 50-100 stuff and while doing that I’m going through and getting some more of the flavor by doing side quests in the areas that I’m spending time in.
I remember having such high hopes for DEMIGOD which this was the box art for. Definitely haven’t thought about it in a long time.